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Product Info Summary
| SKU: | A09894 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, WB |
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Product info
Product Name
Anti-2A5B PPP2R5B Antibody
SKU/Catalog Number
A09894
Size
100ul
Form
Liquid
Description
Boster Bio Anti-2A5B PPP2R5B Antibody catalog # A09894. Tested in ELISA, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-2A5B PPP2R5B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09894)
Host
Rabbit
Contents
Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human 2A5B protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A09894 is reactive to PPP2R5B in Human
Applications
A09894 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
57.393kDa
Background of PPP2R5B
Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Mediates deubiquitination of 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains. Also able to hydrolyze 'Lys-11'-linked ubiquitin chains. Cleaves both polyubiquitin and di-ubiquitin.
Ota T., Nat. Genet. 36:40-45(2004).
Gregory S.G., Nature 441:315-321(2006).
Mural R.J., Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-2000 ELISA 1:5000-20000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For PPP2R5B (Source: Uniprot.org, NCBI)
Gene Name
PPP2R5B
Full Name
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Weight
57.393kDa
Superfamily
phosphatase 2A regulatory subunit B56 family
Alternative Names
B56B; FLJ35411; PP2A B subunit isoform B56-beta; PP2A B subunit isoform B'-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; PR61B; protein phosphatase 2, regulatory subunit B (B56), beta isoform; protein phosphatase 2, regulatory subunit B', beta isoform; protein phosphatase 2, regulatory subunit B', beta; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, betaisoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform PPP2R5B B56B, B56beta, PR61B protein phosphatase 2 regulatory subunit Bbeta serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform|protein phosphatase 2 regulatory subunit B, beta
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PPP2R5B, check out the PPP2R5B Infographic
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In this infographic, you will see the following information for PPP2R5B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-2A5B PPP2R5B Antibody (A09894)
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No publications found for A09894
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